House vacation rentals in Pickens County
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Top-rated house rentals in Pickens County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Pickens County house rentals
House rentals with a pool
Home in Pendleton
4.65 out of 5 average rating, 17 reviewsThe Hawks Nest
Home in Salem
5 out of 5 average rating, 13 reviewsLakefront, Dog Friendly, Golf Resort Amenities
Home in Salem
4.93 out of 5 average rating, 14 reviewsNewly Updated | Lake Keowee | Pool | Amenities
Home in Pickens
5 out of 5 average rating, 10 reviewsTable Rock Retreat - Pool Home In the Mountains
Home in Salem
4.88 out of 5 average rating, 17 reviewsLake Keowee condo by marina&pool close to Clemson
Home in Six Mile
4.9 out of 5 average rating, 29 reviewsLake Keowee Access-Dock-Pool-Grill-Clemson 17 Min
Home in Six Mile
5 out of 5 average rating, 4 reviewsClemson football 15 minutes away. 2 night minimum.
Weekly house rentals
Home in Pendleton
4.87 out of 5 average rating, 54 reviewsBasement apartment in Pendleton w/ sep. entrance
Home in Pendleton
4.98 out of 5 average rating, 58 reviewsRaven's Ridge
Home in Seneca
4.97 out of 5 average rating, 71 reviewsHanover Haven 3 BR/2 Bath
Home in Six Mile
5 out of 5 average rating, 26 reviewsLakefront luxury home w/panoramic view & Boat Slip
Home in Clemson
4.97 out of 5 average rating, 60 reviewsClemson Family 3-bedroom Home Minutes From Campus
Home in Six Mile
4.96 out of 5 average rating, 82 reviewsLake Keowee waterfront private cove Close 2Clemson
Home in Central
5 out of 5 average rating, 10 reviewsFrankie’s Place
Home in Salem
4.85 out of 5 average rating, 13 reviewsKeowee's Peaceful Place
Private house rentals
Home in Seneca
5 out of 5 average rating, 16 reviewsRetreat w/ Dock & Hot Tub at Martin Creek
Home in Six Mile
4.92 out of 5 average rating, 39 reviewsLakefront 5bed with outdoor areas, dock and kayaks
Home in Travelers Rest
4.9 out of 5 average rating, 21 reviewsThe Gathering Spot is a short ride to everywhere!
Home in Six Mile
4.97 out of 5 average rating, 31 reviewsCozy Foothills Retreat
Home in Six Mile
5 out of 5 average rating, 9 reviewsLake Keowee SC Lakehouse Escape
Home in Clemson
4.99 out of 5 average rating, 71 reviews5 BR/5BA house in the heart of Clemson
Home in Central
5 out of 5 average rating, 5 reviewsGames and Vacation Home Clemson !
Home in Clemson
5 out of 5 average rating, 24 reviewsVaulted Ceilings & Accent Windows--1 mile from CU
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