Guesthouse vacation rentals in South Carolina
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Top-rated guesthouse rentals in South Carolina
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Townville
Lisa’s Lodge
Guesthouse in Salem
Mountain Edge Loft
Guesthouse in Greenville
Historic 19th Century Cabin/Guest House
Guesthouse in North Charleston
The Park Circle Clerestory Studio Guest House
Guesthouse in Camden
Red Roof Loft @ FireFly Farm
Guesthouse in Beaufort
Meridian Rd. Guest House Walk to Restaurants/Parks
Guesthouse in Pawleys Island
Private Studio Apt - (Pets/beach/pool/golf)
Guesthouse in Charleston
Mother in Law in James Island Riverland Terrace
Guest house rentals with a patio
Guesthouse in Abbeville
1-bedroom guesthouse in Abbeville, SC
Guesthouse in Charleston
Quaint Cottage Studio in Ashley Forest (Avondale)
Guesthouse in Columbia
Renovated One Bedroom Guest House by UofSC
Guesthouse in Charleston
Studio Apartment Minutes to Downtown Charleston
Guesthouse in Johns Island
Cozy Cottage! 5 mins from Kiawah!
Guesthouse in Charleston
Private Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Spartanburg
The Lodge at Pythian Park
Guesthouse in Campobello
Bungalow on a 3 acre mini farm
Guest house rentals with a washer and dryer
Guesthouse in Abbeville
Modern Carriage House
Guesthouse in Charleston
Cute, Cozy, Charleston Cottage
Guesthouse in Florence
Boho Private Downtown Stay Near I-95 & Hospital
Guesthouse in Mount Pleasant
Guesthouse Convenient to Charleston, Shem Creek, and Beaches
Guesthouse in Westminster
Lit'l Bit O' Heaven- Rocky Top Lodge
Guesthouse in Florence
Midtown Retreat - Guest House in heart of Florence
Guesthouse in Camden
Camden Coach House Long term stay southern balance
Guesthouse in Mount Pleasant
Beach, downtown, Alhambra Hall weddings so close!
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