Guesthouse vacation rentals in Durham

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Top-rated guesthouse rentals in Durham

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Guest favorite

Guesthouse in Fuquay Varina

4.94 out of 5 average rating, 233 reviews

Carriage House at Bracken in Downtown Location

New, private and quiet colonial Carriage House overlooking a park in historic downtown Fuquay-Varina. A lovely half mile walk to both Fuquay and Varina town centers with easy access to eateries, breweries and boutiques. Kitchen has full fridge, microwave, toaster oven, sink, 2 burner cooktop, Keurig with milk frother, coffee and tea supplies, cooking utensils, pots, pans, silverware, breakfast table and chairs. Our place has a queen bed, antique tall boy dresser, oak rocking chair, couch, and TV

Guest favorite

Guesthouse in Cary

4.99 out of 5 average rating, 278 reviews

Cary Downtown on the Park Studio Loft

In Cary's Cultural Arts District. BEST LOCATION IN CARY!!! ON THE NEW DOWNTOWN PARK. Amongst many eateries, pubs, venues, etc. See photos-Guide Book in listing. Free on-site parking. Quiet loft studio modern design, construction in separate building away from busy-noisy streets. On quaint alley w/ parking. Located directly across from new $65M park. BEST LOCATION IN THE RALEIGH- DURHAM AREA. 15 mins. to airport, RTP, Raleigh, NC State, PNC Arena. 30 mins. to Duke, Durham, UNC Chapel Hill.

Guest favorite

Guesthouse in Hillsborough

4.97 out of 5 average rating, 198 reviews

CFCB cabin retreat minutes from Duke, NCCU, & UNC

Cozy, wheelchair-accessible, recently renovated cabin with unique decor and a sitting porch, located in a beautiful, mature, piedmont forest that abounds with wildlife and has hiking trails along New Hope Creek. Ideal for a quiet retreat but only 8 minutes from UNC Hospital, Hillsborough Campus and within 15 to 25 minutes from Duke University, University of North Carolina at Chapel Hill, North Carolina Central University and historic downtown Hillsborough. Guests of all walks of life welcome.

Guest favorite

Guesthouse in Durham

4.95 out of 5 average rating, 259 reviews

Modern Cottage With a Vintage Twist Near Downtown

Come stay at our modern vintage guesthouse in Historic Trinity Park. Our cottage has all modern appliances with vintage fixtures. This 380 square foot cottage is located in a very lively and safe neighborhood just minutes from downtown Durham. Walk one mile on the Ellerbe creek trail to downtown and enjoy all the great entertainment Durham has to offer. Walk 1.5 mile to 9th street restaurants and shops 1 mile to Central Park and farmers market <1 mile to bars and restaurants on geer street

Guest favorite

Guesthouse in Durham

4.99 out of 5 average rating, 373 reviews

Light-filled Guesthouse Near Duke

Best of both worlds--a new garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

Guest favorite

Guesthouse in Saxapahaw

4.92 out of 5 average rating, 709 reviews

The Yurt at Frog Pond Farm

Our yurt (30' dia.) is rustic, beautiful, quiet, in deep woods with deck overlooking pond. Great for couples, small families (not childproof). Includes hot tub & Poetry Walk. Beds are futons. It's warm June-Aug. (no A/C, plenty fans), but way cooler than the city. It's cold Nov.-March (wood stove heat). Mini-fridge & microwave (no kitchen/plumbing). Bath-house is 2-min. walk (toilet, sink, shower). Two minutes to Saxapahaw. Read description for more info. SERIOUSLY NO PARTIES. And no dogs.

Guest favorite

Guesthouse in Durham

4.95 out of 5 average rating, 128 reviews

Spotless Scent & Mold-Free Guesthouse Near Duke!

New-construction (2022) spotlessly clean farmhouse-style guesthouse is 3 mins to Duke, 15 mins to UNC and 25 mins to Raleigh. Perfect for an RTP work trip or weekend alumni or family/student visit. Explore Durham (8 min drive to downtown Durham, DPAC, American Tobacco, etc.) or anywhere in the Triangle from this South Durham location in the charming Tuscaloosa-Lakewood neighborhood. Walking distance to Cocoa Cinnamon coffee shop and restaurants serving breakfast, lunch and dinner.

Guest favorite

Guesthouse in Cary

5 out of 5 average rating, 118 reviews

Guest House on the Cary Downtown Park!

The Park House is a one bedroom guest house located on the new Downtown Cary Park with a luxury king bed, comfy sleeper sofa, two HD SmartTVs, high speed wifi, full kitchen, & more! The beautiful reclaimed wood island doubles as a work area and there is an additional small desk in the bedroom. With walkable access to downtown shops and brew-pubs, dedicated parking and secure self check-in, The Park House in the heart of Cary, is perfect for get-aways or extended business stays!

Guest favorite

Guesthouse in Raleigh

4.94 out of 5 average rating, 260 reviews

Raleigh Oasis Close to it All

The pool is OPEN. Pack your swimsuit! Construction Discount in effect (see the Guest Safety section below) An owner-occupied private residence with a large pool and guesthouse above the detached garage. Enjoy the sights and sounds of a stocked koi pond or observe nature from the private balcony. Minutes from Rex Hospital, Crabtree Mall, Art Museum and PNC arena, the location cannot be beat. Feel far from the city while close to all of the things Raleigh/Durham have to offer.

Guest favorite

Guesthouse in Durham

4.86 out of 5 average rating, 159 reviews

Lovely Studio with King Sized Trmpur-Pedic

Experience the beauty of Duke Forest in your back yard! Cozy and quiet in the trees, yet 2 miles from Duke University. King sized tempur-pedic for an amazing nights sleep. Our wonderful studio apartment boasts a well-equipped kitchenette, Roku with Hulu, Netflix included. A beautiful, private deck with panoramic views of Duke Forest. Walk right onto Sheperd's Trail, curated by Duke University, from the back yard. 2 miles to Duke Hospital. 3 miles to downtown Durham.

Guest favorite

Guesthouse in Chapel Hill

4.96 out of 5 average rating, 347 reviews

Cozy Secluded Accessible West Wing

The West Wing is guest quarters to a residence on 15 acres 5 miles south of Chapel Hill. It's an easy 10 minutes (5 miles) to downtown Chapel Hill, UNC, UNC Hospitals and Carrboro. Comfortable, clean, attractive, and very secluded. It is a studio apartment with one double bed, perfect for one person, cozy for two.. Your friendly, well behaved dog is welcome, but don't ever let your dog on the furniture or leave your dog alone uncrated. Sorry, no cats.

Guest favorite

Guesthouse in Durham

4.95 out of 5 average rating, 814 reviews

Tiny House in the Trees, in the heart of Durham

You'll sleep in a loft nestled in the trees, and wake up to the songs of the morning birds. Super comfy and whimsical, the tiny house has everything you'll need in 120 TINY square feet of charm, right in our backyard in case you need anything at all. The space can accommodate a max of two guests. * This cozy spot is for folks who like it simple, small, rustic and sweet. * * Intentionally, there are no window coverings except for on the kitchen window.*

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Durham guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

Guest favorite

Guesthouse in Five Points

4.87 out of 5 average rating, 442 reviews

Adorable 1BR studio in Five Points

Superhost

Guesthouse in Carrboro

4.85 out of 5 average rating, 414 reviews

Guest cottage close to downtown Carrboro

Guest favorite

Guesthouse in Hillsborough

4.96 out of 5 average rating, 341 reviews

Hummingbird Retreat

Guest favorite

Guesthouse in Cary

4.92 out of 5 average rating, 302 reviews

Central to Everything, Renovated, Dog Friendly.

Guest favorite

Guesthouse in Apex

4.92 out of 5 average rating, 356 reviews

Country place close to all Triangle locations

Guest favorite

Guesthouse in Raleigh

4.98 out of 5 average rating, 910 reviews

Walk to downtown. Private stylish studio cottage.

Guesthouse in Durham

4.87 out of 5 average rating, 181 reviews

Rockwood Oasis Studio BR Full Bath no kitchen

Guest favorite

Guesthouse in Five Points

4.98 out of 5 average rating, 93 reviews

Charming Cottage House in Historic Raleigh

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Guest house rentals with a patio

Guest favorite

Guesthouse in East Raleigh

4.99 out of 5 average rating, 147 reviews

Downtown Private Oasis w/ Cal King

Guest favorite

Guesthouse in Raleigh

4.89 out of 5 average rating, 140 reviews

Retreat La Cabana

Guest favorite

Guesthouse in Durham

5 out of 5 average rating, 13 reviews

New Apt- walk to everything Rockwood

Guest favorite

Guesthouse in Durham

4.98 out of 5 average rating, 89 reviews

Great Guesthouse Studio Suite w/ hot tub & pool!

Guest favorite

Guesthouse in Chapel Hill

4.9 out of 5 average rating, 58 reviews

The cozy home

Guest favorite

Guesthouse in Durham

5 out of 5 average rating, 19 reviews

“Meelie Doll”~ Private - Cozy Stdio Apt abv garage

Guest favorite

Guesthouse in North Raleigh

5 out of 5 average rating, 35 reviews

Carriage House Studio in Quiet Neighborhood

Guest favorite

Guesthouse in Holly Springs

5 out of 5 average rating, 90 reviews

"Wit's End" welcomes you! 2BR comfy guest house

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Guest house rentals with a washer and dryer

Guest favorite

Guesthouse in Raleigh

4.95 out of 5 average rating, 136 reviews

Changes In Latitudes Pool & Suite Raleigh NC.

Guest favorite

Guesthouse in Wake Forest

5 out of 5 average rating, 144 reviews

2 BR, 1.5 BA Guest House on 2-acre wooded lot

Guest favorite

Guesthouse in Raleigh

4.99 out of 5 average rating, 142 reviews

Modern Retreat near Downtown Raleigh

Guest favorite

Guesthouse in Durham

5 out of 5 average rating, 59 reviews

Delightfully Durham: Guesthouse with Kitchen!

Superhost

Guesthouse in Durham

4.91 out of 5 average rating, 94 reviews

Adorable + private guesthouse close to downtown

Guest favorite

Guesthouse in Durham

4.91 out of 5 average rating, 65 reviews

Duke Park Carriage house - Studio

Guest favorite

Guesthouse in Durham

4.84 out of 5 average rating, 38 reviews

Professor's Cottage in Duke Park.

Guest favorite

Guesthouse in Durham

5 out of 5 average rating, 17 reviews

1 Bedroom Apartment Overlooking Duke Campus East

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Quick stats about guesthouse rentals in Durham

Total rentals
40 properties
Total number of reviews
3.9K reviews
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
40 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
Local attractions
Durham Bulls Athletic Park, Brier Creek Commons, and American Tobacco Campus

Guesthouse vacation rentals in Durham

Top-rated guesthouse rentals in Durham

Vacation rentals for every style

Houses

Cabins

Cottages

Popular amenities for Durham guesthouse rentals

Family-friendly guest house rentals

Guesthouse in Five Points

Guesthouse in Carrboro

Guesthouse in Hillsborough

Guesthouse in Cary

Guesthouse in Apex

Guesthouse in Raleigh

Guesthouse in Durham

Guesthouse in Five Points

Guest house rentals with a patio

Guesthouse in East Raleigh

Guesthouse in Raleigh

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Chapel Hill

Guesthouse in Durham

Guesthouse in North Raleigh

Guesthouse in Holly Springs

Guest house rentals with a washer and dryer

Guesthouse in Raleigh

Guesthouse in Wake Forest

Guesthouse in Raleigh

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Durham

Quick stats about guesthouse rentals in Durham

Total rentals

Total number of reviews

Rentals with dedicated workspaces

Wifi availability

Popular amenities

Local attractions

Destinations to explore