House vacation rentals in Durham County

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Top-rated house rentals in Durham County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Durham

4.92 out of 5 average rating, 108 reviews

Coveted family neighborhood close to Duke/Hospital

This remodeled inviting property is close to amenities such as public golf course, Downtown Durham, public parks, shopping, and I-85. Enjoy walking trails down the block or grabbing a round of golf around the corner or visiting unique shops, museums and restaurants nearby. Located close to hospitals. Perfect for 2-4 adults or a small family, includes a fully fenced backyard. Pre-approved dogs are limited to 2. There is a $125 charge. Close to Duke and VA Hospitals as well as rehab centers.

Guest favorite

Home in Durham

4.87 out of 5 average rating, 210 reviews

Woodland Retreat near Duke/Downtown Durham/Eno Riv

Relax in this quaint neighborhood home tucked away in the trees. With a spacious front porch and glass doors onto deck in private backyard, this open yet cozy cottage offers the best of both worlds. Located within 5 mins of Duke Regional and Eno River State Park, close to Duke University and Hospital as well as downtown Durham. Come relax and enjoy all Durham and the RTP has to offer. This private home has a first floor bedroom and full bath as well as two more bedrooms and a full bath upstairs.

Guest favorite

Home in Durham

4.9 out of 5 average rating, 394 reviews

The Bird's Nest

This newly renovated lower level apartment is nestled in the peaceful Forest Hills neighborhood. Our space is in an ideal location to enjoy all that Durham has to offer and comes complete with everything you'll need to feel at home. Minutes from excellent restaurants, outdoor fun, and cultural entertainment. Enjoy an evening at DPAC, a Durham Bulls baseball game, an energizing game of tennis at Forest Hills park, or a relaxing stroll through Duke Gardens. All just minutes from our doorstep.

Superhost

Home in Bahama

4.85 out of 5 average rating, 252 reviews

Cozy & relaxing cottage on the lake *Dog Friendly*

Cozy Lake cottage on the Little River Lake. Come relax on the porch with your coffee in the mornings or take an afternoon nap on the hammock. Fish for a little in the afternoon or go down to the Little River Lake Facility and rent a canoe. It’s the perfect get away that is still close to town and wonderful restaurants. Up to two well behaved and vaccinated dogs are welcome on the property. Dog fee $75 for up to two dogs. Sorry, no cats due to allergies. Swimming is not allowed in the lake.

Guest favorite

Home in Durham

4.96 out of 5 average rating, 290 reviews

Reclaimed Beauty in Downtown's Cleveland-Holloway

Stay in a renovated, simplified Queen Anne-style home from 1915, located on the edge of Durham's Cleveland Holloway neighborhood with easy access to downtown's farmers market, restaurants, and bars. A portion of your stay goes to Airbnb.org to support hosting refugees. Relax in a spacious kitchen with Little Waves coffee, high ceilings, a beautiful live edge slab table, and a luxurious clawfoot tub shower. Please note, there is only one bathroom located in the master bedroom.

Guest favorite

Home in Durham

4.97 out of 5 average rating, 115 reviews

Picket Cottage (See also: Backyard Picket Cottage)

3 BR/2BA charming cottage with easy outdoor access to incredible bkyd w/lg deck, grill, firepit, play set . Fully equipped kitchen, laundry. Dining tables indoor and out. 2 TVs. Spacious study w/2 desks, fast internet, bookcases, reading chair. For kids - toys, pack n'play, high chair. Dogs allowed by approval. 5 min to Duke, 10 min to UNC, 20 min to RDU airport. Additional BR & BA in tiny house w/separate entrance and fenced yard in back available to rent also.

Guest favorite

Home in Durham

4.93 out of 5 average rating, 151 reviews

Cozy home 2mi from DPAC & Duke Hospital!

Adorable dog friendly cottage in the heart of Walltown, one of the classic neighborhoods that drive Durham's popularity. One block from Duke East Campus, three blocks from the bars and cafes of 9th street, & a short Uber or Lyft to downtown or Duke hospital. The small cottage is full of charm and character with open kitchen and living area with granite counters, tiled kitchen and bath, and back screened porch. It offers Central heat and air, dishwasher, washer/dryer.

Guest favorite

Home in Durham

4.85 out of 5 average rating, 163 reviews

CHARM & Convenience!! 3Br Cottage-Style Ranch

This home is located in the more DESIRABLE and 'not as congested' low crime area of Durham near Chapel Hill, on a half acre lot in the rural buffer zone! You're really convenient to Duke Hospital/Duke campus, and also just a very short drive to Chapel Hill! The backyard is BIG and completely fenced in for family games or just enjoying the birds, or your dog's exercise! Duke Forest trails and New Hope Creek are VERY nearby for a wonderful hike during your stay.

Guest favorite

Home in Durham

4.95 out of 5 average rating, 175 reviews

Cheerful 3 BR home in South Durham near everything

You'll be close to everything at this centrally-located South Durham home on a quiet cul de sac. Brand new flooring throughout the house! Dog friendly with a spacious fenced in back yard and screened in porch. The house is located one mile from the main highway and 10-20 minutes from Duke, UNC, Raleigh, RTP and more. You'll also be walking distance from a playground, dog park, grocery stores, restaurants, local coffee shop, and the Tobacco Trail.

Guest favorite

Home in Chapel Hill

4.98 out of 5 average rating, 115 reviews

Heart of Chapel Hill

One bedroom suite located in quiet residential area of Chapel Hill. Walking distance to University Place, Whole Foods and Trader Joe’s. Just three miles from UNC campus with quick access to RTP/Durham/Raleigh. Separate gated entrance with keyless access. Queen sized bed with private kitchenette, washer/dryer and bathroom. Private patio with grill and seating. On street parking. No cleaning fee. 3:00 pm ET check-in. CH Permit # STR-23-43

Guest favorite

Home in Durham

4.92 out of 5 average rating, 114 reviews

2 Bedroom-Bull City Guest House near Duke/Downtown

Spacious 2 bedrooms with queen bed / 1 full bath, dining room, full kitchen, living room Strong Wi-Fi, Roku TV, smart-lock, dishes, pots and pans, etc. Everything you need for a memorable stay in Bull City! Distances: Duke University Main Campus - 1.6 miles Duke Hospital - 2.1 miles American Tobacco Campus / DPAC / Durham Bulls Ball Park - 4.8 miles Downtown Durham / Brightleaf Square 5.1 Miles

Guest favorite

Home in Durham

4.92 out of 5 average rating, 179 reviews

Fenced-DownTown-Pets-Great Reviews

Bungalow on a fenced corner lot. Pet friendly with a big beautiful tree in the front yard. Outdoor sitting area and fire pit. Fast Internet. 55" HD 4K Roku TV. Remodeled bathroom. New very comfy beds and pillows. Hardwood floors. Blackout Curtains in both bedrooms for deep sleep. Fully stocked ready-to-cook small kitchen. Washer and dryer. No dishwasher.