House vacation rentals in Mesilla
Find and book unique houses on Airbnb
Top-rated house rentals in Mesilla
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesilla house rentals
House rentals with a pool
Home in Las Cruces
4.93 out of 5 average rating, 271 reviewsCasita at the Mediterranean Palms Estate
Home in Las Cruces
4.9 out of 5 average rating, 105 reviewsAlamo on Ocotillo
Home in Las Cruces
4.96 out of 5 average rating, 80 reviewsDesert Oasis with Pool
Home in Las Cruces
4.84 out of 5 average rating, 43 reviewsCheerful 3 bedroom home with spectacular pool!
Home in Las Cruces
5 out of 5 average rating, 71 reviewsSpacious and clean 4-BR home with pool & hot tub
Home in Las Cruces
4.65 out of 5 average rating, 65 reviewsCentrally located with great outdoor living space.
Home in Las Cruces
4.98 out of 5 average rating, 81 reviewsYear Round Heated Pool, Fast Wifi, Pet Friendly
Home in Las Cruces
5 out of 5 average rating, 58 reviewsYour own personal resort, pool, spa, putting green
Weekly house rentals
Home in Las Cruces
4.95 out of 5 average rating, 327 reviewsCasa Blanca de Las Cruces
Home in Las Cruces
4.87 out of 5 average rating, 150 reviewsCasa La Jolla
Home in Las Cruces
4.84 out of 5 average rating, 144 reviewsVIGIL-INN High Desert Escape in Quiet Neighborhood
Home in Las Cruces
4.91 out of 5 average rating, 129 reviews4BR/2.5BA w/ Fully operational Hot tub - Near NMSU
Home in Las Cruces
4.97 out of 5 average rating, 151 reviewsModern Hidden Gem- HOT TUB & Organ Mtn Views/Patio
Home in Las Cruces
5 out of 5 average rating, 18 reviewsPurple Sage Garden Retreat
Home in Las Cruces
4.8 out of 5 average rating, 40 reviewsCozy three bedroom close to the University
Home in Las Cruces
4.92 out of 5 average rating, 65 reviewsSpacious Southwest Retreat. king bed!
Private house rentals
Home in Las Cruces
4.8 out of 5 average rating, 10 reviewsGreat little home.
Home in Las Cruces
4.83 out of 5 average rating, 30 reviewsLas Cruces Stylish Full House
Home in Las Cruces
4.89 out of 5 average rating, 57 reviewsLotus Blossom: serene, quiet, relaxing!
Home in Las Cruces
5 out of 5 average rating, 36 reviewsSouth Western style home with hot tub
Home in Las Cruces
4.9 out of 5 average rating, 49 reviewsCozy adobe home close to downtown with hot tub!
Home in Las Cruces
4.99 out of 5 average rating, 91 reviewsBeautiful new home features 3BD 3 bath
Home in Las Cruces
5 out of 5 average rating, 3 reviewsSouthwestern Comfort Stay 1
Home in Las Cruces
5 out of 5 average rating, 64 reviewsModern Farmhouse Near Bike Path
Quick stats about house rentals in Mesilla
Total rentals
20 properties
Nightly prices starting at
$60 before taxes and fees
Total number of reviews
1.8K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Wifi availability
20 properties include access to wifi
Destinations to explore
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