Guesthouse vacation rentals in Frederick County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Frederick County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
0 of 0 items showing
1 of 3 pages
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Frederick County guesthouse rentals
Family-friendly guest house rentals
Guest favorite
Guesthouse in Frederick
4.88 out of 5 average rating, 32 reviewsThe Wander Inn
Guest favorite
Guesthouse in Smithsburg
4.97 out of 5 average rating, 701 reviewsJewel Vinsota Artist's Guesthouse
Guest favorite
Guesthouse in Frederick
4.98 out of 5 average rating, 173 reviewsRomantic Getaway - Heated Spa Open Year Round
Guest favorite
Guesthouse in Frederick
4.97 out of 5 average rating, 328 reviewsThe Shady Bear Cabin
Guest favorite
Guesthouse in Middletown
4.95 out of 5 average rating, 274 reviewsIndulge, Fresh Flowers, Frederick County Haven
Guest house rentals with a washer and dryer
Guest favorite
Guesthouse in Keymar
4.98 out of 5 average rating, 57 reviewsHistoric country guesthouse, newly renovated.
Guest favorite
Guesthouse in Myersville
4.93 out of 5 average rating, 227 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
Guest favorite
Guesthouse in Mount Airy
4.97 out of 5 average rating, 105 reviewsTreasured Hideaway on the Hill
Guest favorite
Guesthouse in Lovettsville
4.94 out of 5 average rating, 16 reviewsThe Tuberose Suite
Guest favorite
Guesthouse in Frederick
4.88 out of 5 average rating, 32 reviewsThe Wander Inn
Guest favorite
Guesthouse in Smithsburg
4.97 out of 5 average rating, 701 reviewsJewel Vinsota Artist's Guesthouse
Guest favorite
Guesthouse in Frederick
4.98 out of 5 average rating, 173 reviewsRomantic Getaway - Heated Spa Open Year Round
Guest favorite
Guesthouse in New Windsor
5 out of 5 average rating, 17 reviewsGuesthouse at Toccoa Homestead
Destinations to explore
- Guesthouse rentals United States
- House rentals United States
- House rentals Washington
- Guesthouse rentals Washington
- House rentals Deep Creek Lake
- House rentals Baltimore
- Guesthouse rentals Baltimore
- House rentals Maryland
- Guesthouse rentals Maryland
- Rentals with a fireplace Frederick County
- Pet-friendly rentals Frederick County
- Rentals with a hot tub Frederick County
- Rentals with pools Frederick County
- House rentals Frederick County
- Farmstay rentals Frederick County
- Rentals with lake access Frederick County
- Apartment rentals Frederick County
- Kid-friendly rentals Frederick County
- Monthly Rentals Frederick County
- Rentals with a patio Frederick County
- Rentals with a washer and dryer Frederick County
- Rentals with a fire pit Frederick County
- Rentals with outdoor seating Frederick County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom