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House vacation rentals in Cape Girardeau
Find and book unique houses on Airbnb
Top-rated house rentals in Cape Girardeau
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Cape Girardeau house rentals
House rentals with a pool
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Home in Cape Girardeau
4.71 out of 5 average rating, 198 reviews3+ acre: Swimming Pool/Mini Golf/Pool Table/Nature
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Home in Cobden
4.92 out of 5 average rating, 38 reviewsSkyline Getaways
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Home in Murphysboro
5 out of 5 average rating, 73 reviewsEmbers of Murphysboro
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Home in Farmington
4.8 out of 5 average rating, 15 reviews3-bedroom, 2.5-bath 'Barn Loft'
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Home in Park Hills
4.98 out of 5 average rating, 57 reviewsBluebird Meadows w/ Hot Tub and Pool **Special***
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Home in Du Quoin
4.8 out of 5 average rating, 25 reviewsPeninsula Paradise - South
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Home in Creal Springs
4.91 out of 5 average rating, 11 reviewsLake Views & Access + Private Pool, Pets OK
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Home in Du Quoin
4.89 out of 5 average rating, 140 reviewsMarsha's Guesthouse Rental
Weekly house rentals
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Home in Tunnel Hill
5 out of 5 average rating, 272 reviewsPole Barn Cabin Lake of Egypt ~ Hottub Wineries
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Home in Clinton
4.99 out of 5 average rating, 145 reviewsThe Peery House at Springhill Farms
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Home in Carterville
4.91 out of 5 average rating, 300 reviewsNewly Updated Family Home in Carterville
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Home in Bloomsdale
4.95 out of 5 average rating, 116 reviewsHop off the highway, Relax!
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Home in Macedonia
4.97 out of 5 average rating, 231 reviewsOff the Beatn Path. Close to Hunting/Fishing.
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Home in Marion
4.8 out of 5 average rating, 577 reviewsFrank Lloyd Wright design inspired house
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Home in Carbondale
5 out of 5 average rating, 526 reviewsCharming 3 bedroom bungalow in Downtown Carbondale
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Home in Metropolis
4.93 out of 5 average rating, 107 reviewsThe Farm on Deer Run
Private house rentals
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Home in Cape Girardeau
4.91 out of 5 average rating, 44 reviewsCozy Cottage
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Home in Cape Girardeau
4.86 out of 5 average rating, 64 reviewsDowntown Home steps away from Food and Fun
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Home in Cape Girardeau
5 out of 5 average rating, 9 reviewsCapeG Historic Home [downtown]
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Home in Cape Girardeau
4.79 out of 5 average rating, 33 reviews3 Bed Bungalow w/ Deck and Fenced-In Back Yard
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Home in Cape Girardeau
4.95 out of 5 average rating, 22 reviewsCharming 2-Story- C.1847 - River Views - Fast Wifi
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Home in Anna
5 out of 5 average rating, 7 reviews150 year old charmer!
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Home in Bloomfield
4.92 out of 5 average rating, 39 reviewsBloomfield Bungalow
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Home in Ozark
4.99 out of 5 average rating, 76 reviewsThe Little Red Inn
Quick stats about house rentals in Cape Girardeau
Total rentals
80 properties
Nightly prices starting at
$30 before taxes and fees
Total number of reviews
3.1K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
50 properties have a dedicated workspace
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